Following is a list of big differences between them.
||AnglarJS is an open source web application development framework developed by Google.
||You have to install Node.js on your computer system to use it further for creating web or chat applications.
||Node.js supports non-blocking input output I/O and follows an event driven architecture. It is used to create real-time applications such as instant messaging or chat apps.
||Node.js has a lot number of frameworks such as Express.js, Sails.js, Partial.js etc.